Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0H1LK
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| Former ID |
DNC004526
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| Drug Name |
3-(4-Amino-phenyl)-pyrrolidine-2,5-dione
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| Synonyms |
32856-49-8; 3-(4-Amino-phenyl)-pyrrolidine-2,5-dione; 3-(4-aminophenyl)pyrrolidine-2,5-dione; 3-(4-Aminophenyl)-2,5-pyrrolidinedione; CHEMBL148903; 2,5-Pyrrolidinedione, 3-(4-aminophenyl)-; WSP-3; 3-(4'-aminophenyl)pyrrolidine-2,5-dione; AC1Q6LVA; 2-(p-aminophenyl) succinimide; SCHEMBL3274268; AC1L4Q15; CTK4G9448; BDBM50025154; FCH920777; AKOS006343465; AB07636; CC-12440; KB-26942; AS-35730; 2,5-Pyrrolidinedione,3-(4-aminophenyl)-; AX8033232; AB0073720; FT-0691904; X-3375; C-33345; 3-(4-amino-phenyl)-pyrrolidine-2,5-dione, AldrichCP
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H10N2O2
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| Canonical SMILES |
C1C(C(=O)NC1=O)C2=CC=C(C=C2)N
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| InChI |
1S/C10H10N2O2/c11-7-3-1-6(2-4-7)8-5-9(13)12-10(8)14/h1-4,8H,5,11H2,(H,12,13,14)
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| InChIKey |
AFLGSUFOCCZEEZ-UHFFFAOYSA-N
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| CAS Number |
CAS 32856-49-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aromatase (CYP19A1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Estradiol biosynthesis II | ||||
| Estradiol biosynthesis I | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| Panther Pathway | Androgen/estrogene/progesterone biosynthesis | |||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Reactome | Endogenous sterols | |||
| WikiPathways | Metapathway biotransformation | |||
| Tryptophan metabolism | ||||
| Oxidation by Cytochrome P450 | ||||
| Ovarian Infertility Genes | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| FSH signaling pathway | ||||
| Integrated Breast Cancer Pathway | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biochemical evaluation of analogues of aminoglutethimide based on phenylpyrrolidine-2,5-dione. J Med Chem. 1986 Apr;29(4):520-3. | |||
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