Drug Information
Drug General Information | Top | |||
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Drug ID |
D0H1WN
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Drug Name |
Indoline derivative 8
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Synonyms |
PMID27646439-Compound-16
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Drug Type |
Small molecular drug
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Company |
JANSSEN PHARMACEUTICA NV
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Structure |
Download2D MOL |
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Formula |
C26H21F3N4O3
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Canonical SMILES |
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C4=C(C=C3)N(CC4)C(=O)CC5=C(C=CC(=C5)F)F)F)OC
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InChI |
1S/C26H21F3N4O3/c1-35-22-11-17-20(12-23(22)36-2)30-13-31-26(17)32-19-5-6-21-16(25(19)29)7-8-33(21)24(34)10-14-9-15(27)3-4-18(14)28/h3-6,9,11-13H,7-8,10H2,1-2H3,(H,30,31,32)
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InChIKey |
BJJFQLVMCHTWRM-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | PRKR-like endoplasmic reticulum kinase (PERK) | Target Info | Inhibitor | [1] |
Target's Patent Info | PRKR-like endoplasmic reticulum kinase (PERK) | Target's Patent Info | [1] |
References | Top | |||
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REF 1 | Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Jan;27(1):37-48. |
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