Drug Information
Drug General Information | Top | |||
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Drug ID |
D0H2MF
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Former ID |
DNC010894
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Drug Name |
PF-02367982
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Synonyms |
CHEMBL1083754; BDBM50318934
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Drug Type |
Small molecular drug
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Indication | Endometriosis [ICD-11: GA10; ICD-10: N80, N80.9; ICD-9: 617] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C19H20N4O2
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Canonical SMILES |
CNC(=O)CN1C(=C(C(=N1)C2CC2)OC3=CC=C(C=C3)C#N)C4CC4
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InChI |
1S/C19H20N4O2/c1-21-16(24)11-23-18(14-6-7-14)19(17(22-23)13-4-5-13)25-15-8-2-12(10-20)3-9-15/h2-3,8-9,13-14H,4-7,11H2,1H3,(H,21,24)
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InChIKey |
PQGLAOODCQDRAR-UHFFFAOYSA-N
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CAS Number |
CAS 913344-84-0
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Progesterone receptor (PGR) | Target Info | Inhibitor | [1] |
KEGG Pathway | Oocyte meiosis | |||
Progesterone-mediated oocyte maturation | ||||
Pathway Interaction Database | Cellular roles of Anthrax toxin | |||
Reactome | Nuclear signaling by ERBB4 | |||
Nuclear Receptor transcription pathway | ||||
WikiPathways | Ovarian Infertility Genes | |||
Signaling by ERBB4 | ||||
Nuclear Receptors |
References | Top | |||
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REF 1 | Optimisation of a pyrazole series of progesterone antagonists; Part 1. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3384-6. |
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