Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0H2OA
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| Former ID |
DNC000186
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| Drug Name |
Alpha-monofluoromethyl-3,4-dehydroornithine ethyl ester
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| Synonyms |
Mdl-72430; 2-(Fluoromethyl)dehydroornithine ethyl ester; AC1O5Q9S; SCHEMBL10981099; 97501-15-0; ethyl (E)-2,5-diamino-2-(fluoromethyl)pent-3-enoate; 3-Pentenoic acid, 2,5-diamino-2-(fluoromethyl)-, ethyl ester
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H15FN2O2
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| Canonical SMILES |
CCOC(=O)C(CF)(C=CCN)N
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| InChI |
1S/C8H15FN2O2/c1-2-13-7(12)8(11,6-9)4-3-5-10/h3-4H,2,5-6,10-11H2,1H3/b4-3+
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| InChIKey |
RQVGWIPBGFYUQU-ONEGZZNKSA-N
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| CAS Number |
CAS 97501-15-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ornithine decarboxylase (ODC1) | Target Info | Inhibitor | [1] |
| BioCyc | Putrescine biosynthesis I | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Panther Pathway | Ornithine degradation | |||
| CCKR signaling map ST | ||||
| Pathwhiz Pathway | Spermidine and Spermine Biosynthesis | |||
| Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Plasmodium falciparum and Plasmodium berghei: effects of ornithine decarboxylase inhibitors on erythrocytic schizogony. Exp Parasitol. 1987 Oct;64(2):237-43. | |||
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