Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0H3EV
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| Former ID |
DNC000116
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| Drug Name |
9-Nitropaullone
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| Synonyms |
Alsterpaullone; alsterpaullone; 237430-03-4; NSC 705701; NSC-705701; CHEMBL50894; MLS002702475; 9-Nitro-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one; 9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one; 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5)-one; 9-NITRO-5,12-DIHYDRO-7H-BENZO[2,3]AZEPINO[4,5-B]INDOL-6-ONE; Paullone Analog 1; AC1NMCUD; Kinome_3754; 1q3w; Alsterpaullone derivative, 2; Lopac0_000057; CBiol_001723; GTPL5925; BDBM7262; SCHEMBL2170104; CTK8F0374; ZINC23894; BDBM84528; DTXSID50407444
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H11N3O3
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| Canonical SMILES |
C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)[N+](=O)[O-]
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| InChI |
1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20)
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| InChIKey |
OLUKILHGKRVDCT-UHFFFAOYSA-N
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| CAS Number |
CAS 237430-03-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
528841, 7403857, 7886004, 8036818, 8531455, 11119890, 11120378, 11120866, 11146973, 11442023, 12015322, 14751398, 24890918, 26758195, 41765935, 46392943, 46504736, 47364899, 47661990, 50424594, 53789994, 57357310, 85787109, 91746588, 92764452, 99302616, 103048092, 103235938, 103905621, 113640480, 121363818, 128827480, 134339637, 135316557, 135364562, 135685140, 136350628, 140243963, 152029045, 160967082, 163125286, 163688633, 175607452, 178102548, 179148378, 184598249, 184605744, 204380408, 208265569, 223454863
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| ChEBI ID |
CHEBI:138488
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5925). | |||
| REF 2 | Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol Sci. 2002 Sep;23(9):417-25. | |||
| REF 3 | Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells. J Biol Chem. 2004 May 7;279(19):20267-76. | |||
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