Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H7AV
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| Former ID |
DIB003538
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| Drug Name |
Pilsicainide
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| Synonyms |
SUNRYTHM; Sunrhythm; Pilsicainide hydrochloride; DU-6552; SUN-1165; SUN-1165i
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| Drug Type |
Small molecular drug
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| Indication | Heart arrhythmia [ICD-11: BC65; ICD-10: I49, I49.8] | Approved | [1] | |
| Company |
Suntory Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C17H24N2O
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| Canonical SMILES |
CC1=C(C(=CC=C1)C)NC(=O)CC23CCCN2CCC3
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| InChI |
1S/C17H24N2O/c1-13-6-3-7-14(2)16(13)18-15(20)12-17-8-4-10-19(17)11-5-9-17/h3,6-7H,4-5,8-12H2,1-2H3,(H,18,20)
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| InChIKey |
BCQTVJKBTWGHCX-UHFFFAOYSA-N
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| CAS Number |
CAS 88069-67-4
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:135127
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Modulator | [1], [2] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | A sodium channel blocker, pilsicainide, produces atrial post-repolarization refractoriness through the reduction of sodium channel availability. Tohoku J Exp Med. 2011;225(1):35-42. | |||
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