Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0HL9S
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| Former ID |
DNC010494
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| Drug Name |
1-(4-Aminobenzyl)-1H-imidazole
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| Synonyms |
56643-85-7; 4-Imidazol-1-ylmethylphenylamine; 4-(1H-imidazol-1-ylmethyl)aniline; 4-((1H-imidazol-1-yl)methyl)aniline; 4-(imidazol-1-ylmethyl)aniline; 4-[(1-Imidazolyl)methyl]aniline; 4-Imidazol-1-ylmethyl-phenylamine; 4-[(1H-Imidazol-1-yl)methyl]aniline; 1-(4-Aminobenzyl)imidazole; CHEMBL598389; 4-(imidazolylmethyl)phenylamine; Benzenamine, 4-(1H-imidazol-1-ylmethyl)-; 1-(4-Aminobenzyl)-1H-imidazole; BAS 06504682; AC1LOLP2; SCHEMBL77025; AC1Q520P; CTK5A5496; DTXSID40361425; 4-(imidazol-1-yl)methyl-aniline
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H11N3
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| Canonical SMILES |
C1=CC(=CC=C1CN2C=CN=C2)N
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| InChI |
1S/C10H11N3/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7,11H2
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| InChIKey |
DGHAOTHIDTUSJY-UHFFFAOYSA-N
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| CAS Number |
CAS 56643-85-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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