Drug Information
Drug General Information | Top | |||
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Drug ID |
D0HQ3A
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Former ID |
DIB015422
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Drug Name |
ELGODIPINE HYDROCHLORIDE
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Synonyms |
IQB-875; Elgodipine hydrochloride; Rac-2,6-Dimethyl-4-(2,3-methylenedioxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-isopropyl 5-[2-[N-(4-fluorobenzyl)-N-methylamino]ethyl] diester monohydrochloride
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Drug Type |
Small molecular drug
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Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Discontinued in Phase 3 | [1] | |
Structure |
Download2D MOL
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Formula |
C29H34ClFN2O6
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Canonical SMILES |
CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=C3C(=CC=C2)OCO3)C(=O)OCCN(C)CC4=CC=C(C=C4)F.Cl
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InChI |
1S/C29H33FN2O6.ClH/c1-17(2)38-29(34)25-19(4)31-18(3)24(26(25)22-7-6-8-23-27(22)37-16-36-23)28(33)35-14-13-32(5)15-20-9-11-21(30)12-10-20;/h6-12,17,26,31H,13-16H2,1-5H3;1H
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InChIKey |
JBKDMKOYLBVOOR-UHFFFAOYSA-N
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CAS Number |
CAS 121489-04-1
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Calcium channel unspecific (CaC) | Target Info | Agonist | [2], [3] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000324) | |||
REF 2 | The calcium channel blocker amlodipine exerts its anti-proliferative action via p21(Waf1/Cip1) gene activation. FASEB J. 2004 Oct;18(13):1516-23. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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