Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I1QF
|
|||
| Former ID |
DIB021157
|
|||
| Drug Name |
vesamicol
|
|||
| Synonyms |
vesamicol; VESAMICOL HYDROCHLORIDE; 22232-64-0; CHEMBL20943; MLS000554350; 2-(4-Phenyl-piperidin-1-yl)-cyclohexanol; Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-; 2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol; AH-5183; 2-(4-Phenyl-1-piperidinyl)cyclohexanol; SMR000146667; 2-(4-Phenylpiperidino)cyclohexanol; 23965-53-9; V-100; Spectrum_000292; Opera_ID_322; AC1Q7BAI; AC1L1KUQ; Prestwick1_000920; Spectrum3_001861; Prestwick0_000920; Prestwick2_000920; Oprea1_778558; Lopac0_001228; Oprea1_695768; KBioSS_000772; BSPBio_003302; MLS001201728
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C17H25NO
|
|||
| Canonical SMILES |
C1CCC(C(C1)N2CCC(CC2)C3=CC=CC=C3)O
|
|||
| InChI |
1S/C17H25NO/c19-17-9-5-4-8-16(17)18-12-10-15(11-13-18)14-6-2-1-3-7-14/h1-3,6-7,15-17,19H,4-5,8-13H2
|
|||
| InChIKey |
YSSBJODGIYRAMI-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 22232-64-0
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
5439765, 8153476, 10590762, 11335551, 11360790, 11363186, 11365748, 11368310, 11372901, 11376472, 11461762, 11466948, 11468068, 11486725, 11491676, 11494106, 14730560, 14774640, 29224699, 47291067, 47515243, 47662208, 48184927, 48259154, 48334414, 50070259, 50070932, 50086378, 50111271, 57322885, 78944731, 85789429, 89033113, 89449663, 90341156, 94557994, 103187093, 103818771, 103929254, 104309887, 105120204, 117618157, 117930112, 124750336, 124800127, 124881785, 126408200, 129842598, 135066574, 137010572
|
|||
| ChEBI ID |
CHEBI:103974
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Vesicular acetylcholine transporter (SLC18A3) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4759). | |||
| REF 2 | Vesamicol analogues as sigma ligands. Molecular determinants of selectivity at the vesamicol receptor. Biochem Pharmacol. 1995 Mar 15;49(6):791-7. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.