Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I4GT
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| Drug Name |
Hexylcarbamoyl fluorouracil
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| Synonyms |
Carmofur; HCFU; Yamaful; 1-hexylcarbamoyl-5-fluorouracil
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| Drug Type |
Small molecular drug
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| Indication | Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Investigative | [1] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C11H16FN3O3
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| Canonical SMILES |
CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F
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| InChI |
1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
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| InChIKey |
AOCCBINRVIKJHY-UHFFFAOYSA-N
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| CAS Number |
CAS 61422-45-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3216171, 7387278, 7848846, 8151702, 11372979, 11483827, 11487842, 11491775, 12013343, 15070136, 26612896, 26679827, 26719870, 26719871, 26749035, 26749036, 26749037, 29221737, 46386675, 46386676, 47662465, 49681689, 50035753, 50122576, 50488595, 57321379, 85246420, 88814485, 92124632, 92308362, 92711699, 99437075, 103090022, 103155025, 103590513, 104300992, 117593300, 118048421, 118844969, 124637533, 124757145, 124891854, 125082095, 125163949, 125354452, 126630606, 126657144, 126685777, 126737761, 127434796
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| ChEBI ID |
CHEBI:31360
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | COVID-19 papain-like proteinase (PL-PRO) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure of Mpro from COVID-19 virus and discovery of its inhibitors. Nature. 2020 Apr 9. | |||
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