Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0I8DW
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| Former ID |
DNC006642
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| Drug Name |
4-nitrophenylsulfamide
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| Synonyms |
4-nitrophenylsulfamide; N-(4-Nitrophenyl)sulfamide; CHEMBL168778; 70466-80-7; AC1LD5GZ; N-(4-Nitrophenyl)sulfamide #; Sulphamide, N-(4-nitrophenyl)-; RAXPQAODVUNKFW-UHFFFAOYSA-N; 1-nitro-4-(sulfamoylamino)benzene; BDBM50124157
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C6H7N3O4S
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| Canonical SMILES |
C1=CC(=CC=C1NS(=O)(=O)N)[N+](=O)[O-]
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| InChI |
1S/C6H7N3O4S/c7-14(12,13)8-5-1-3-6(4-2-5)9(10)11/h1-4,8H,(H2,7,12,13)
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| InChIKey |
RAXPQAODVUNKFW-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements. J Med Chem. 2006 Jun 15;49(12):3496-500. | |||
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