Drug Information
Drug General Information | Top | |||
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Drug ID |
D0IC3K
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Drug Name |
N-phenyl-5-phenyl-pyrazolin-3-yl amide derivative 1
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Synonyms |
PMID26161824-Compound-100
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Drug Type |
Small molecular drug
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Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Patented | [1] | |
Structure |
Download2D MOL |
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Formula |
C23H23Cl3N4O3
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Canonical SMILES |
CCOC(=O)C1CCCN1NC(=O)C2=NN(C(C2)C3=CC=C(C=C3)Cl)C4=C(C=C(C=C4)Cl)Cl
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InChI |
1S/C23H23Cl3N4O3/c1-2-33-23(32)20-4-3-11-29(20)28-22(31)18-13-21(14-5-7-15(24)8-6-14)30(27-18)19-10-9-16(25)12-17(19)26/h5-10,12,20-21H,2-4,11,13H2,1H3,(H,28,31)
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InChIKey |
SXZDWKSALIBFCB-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Antagonist | [1] |
Target's Patent Info | Cannabinoid receptor 1 (CB1) | Target's Patent Info | [1] | |
KEGG Pathway | Rap1 signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Retrograde endocannabinoid signaling | ||||
Panther Pathway | Endogenous cannabinoid signaling | |||
Pathway Interaction Database | N-cadherin signaling events | |||
Reactome | Class A/1 (Rhodopsin-like receptors) | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Small Ligand GPCRs | ||||
BDNF signaling pathway | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents. Expert Opin Ther Pat. 2015 Oct;25(10):1093-116. |
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