Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0IU2K
|
|||
| Former ID |
DNC008611
|
|||
| Drug Name |
YPAA-NH2
|
|||
| Synonyms |
CHEMBL466147; YPAA-NH2
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C20H29N5O5
|
|||
| Canonical SMILES |
CC(C(=O)N)NC(=O)C(C)NC(=O)C1CCCN1C(=O)C(CC2=CC=C(C=C2)O)N
|
|||
| InChI |
1S/C20H29N5O5/c1-11(17(22)27)23-18(28)12(2)24-19(29)16-4-3-9-25(16)20(30)15(21)10-13-5-7-14(26)8-6-13/h5-8,11-12,15-16,26H,3-4,9-10,21H2,1-2H3,(H2,22,27)(H,23,28)(H,24,29)/t11-,12-,15-,16-/m0/s1
|
|||
| InChIKey |
UTONSZTXKQBYQC-APYUEPQZSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor mu (MOP) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Enkephalin release | ||||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | TCR Signaling Pathway | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | ||||
| Opioid Signalling | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Internalisation of the mu-opioid receptor by endomorphin-1 and leu-enkephalin is dependant on aromatic amino acid residues. Bioorg Med Chem. 2008 Apr 15;16(8):4341-6. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.