Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0IV7Z
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| Former ID |
DIB004447
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| Drug Name |
AZD-8418
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| Indication | Schizophrenia [ICD-11: 6A20] | Phase 1 | [1] | |
| Company |
AstraZeneca plc
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H20ClN3O3
|
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| Canonical SMILES |
CC(C1CC1)N2CC3=C(C2=O)C(=CC(=C3)C4=CC(=NO4)C(=O)N(C)C)Cl
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| InChI |
1S/C19H20ClN3O3/c1-10(11-4-5-11)23-9-13-6-12(7-14(20)17(13)19(23)25)16-8-15(21-26-16)18(24)22(2)3/h6-8,10-11H,4-5,9H2,1-3H3/t10-/m0/s1
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| InChIKey |
MCPBSUCAISQZQK-JTQLQIEISA-N
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| CAS Number |
CAS 1198309-73-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01027234) This Study Will Assess the Safety and Tolerability of AZD8418 After Single Increasing Oral Doses. U.S. National Institutes of Health. | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031633) | |||
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