Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0J0RG
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| Former ID |
DIB011965
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| Drug Name |
UK-66914
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| Synonyms |
UK-66914; 113049-11-9; Methanesulfonamide, N-[4-[1-hydroxy-2-[4-(4-pyridinyl)-1-piperazinyl]ethyl]phenyl]-; Methanesulfonamide, N-(4-(1-hydroxy-2-(4-(4-pyridinyl)-1-piperazinyl)ethyl)phenyl)-; UK66914; UK 66914; UK-66,914; AC1MIZ8F; SCHEMBL6375438
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| Drug Type |
Small molecular drug
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| Indication | Cardiac arrhythmias [ICD-11: BC9Z; ICD-9: 427] | Phase 1 | [1] | |
| Company |
Pfizer Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C18H24N4O3S
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| Canonical SMILES |
CS(=O)(=O)NC1=CC=C(C=C1)C(CN2CCN(CC2)C3=CC=NC=C3)O
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| InChI |
1S/C18H24N4O3S/c1-26(24,25)20-16-4-2-15(3-5-16)18(23)14-21-10-12-22(13-11-21)17-6-8-19-9-7-17/h2-9,18,20,23H,10-14H2,1H3
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| InChIKey |
MXVFGNOLZDAKQJ-UHFFFAOYSA-N
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| CAS Number |
CAS 113049-11-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Blocker | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000131) | |||
| REF 2 | Electrophysiologic properties of UK-66,914, a novel class III antiarrhythmic agent. J Cardiovasc Pharmacol. 1991 Mar;17(3):376-85. | |||
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