Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0J2SM
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| Former ID |
DNC014544
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| Drug Name |
2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one
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| Synonyms |
CHEMBL10378; NSC165772; AC1L6PF7; 2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one; SCHEMBL913450; BDBM50063703; NSC-165772; 2-(2-iodophenyl)-3,1-benzoxazin-4-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H8INO2
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=O)OC(=N2)C3=CC=CC=C3I
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| InChI |
1S/C14H8INO2/c15-11-7-3-1-5-9(11)13-16-12-8-4-2-6-10(12)14(17)18-13/h1-8H
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| InChIKey |
VEBIXPCJYGGBAF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cationic trypsinogen (PRSS1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Pancreatic secretion | ||||
| Protein digestion and absorption | ||||
| Influenza A | ||||
| Reactome | Activation of Matrix Metalloproteinases | |||
| Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
| WikiPathways | Activation of Matrix Metalloproteinases | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2-amino-4H-3,1-benzoxazin-4-ones as inhibitors of C1r serine protease. J Med Chem. 1998 Mar 26;41(7):1060-7. | |||
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