Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0J5EF
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| Former ID |
DNC010128
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| Drug Name |
2-(tert-Butylamino)-3'-fluoropropiophenone
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| Synonyms |
2-(tert-butylamino)-1-(3-fluorophenyl)propan-1-one; CHEMBL576063; AC1Q5DGH; AC1L4Y0Z; 2-(tert-butylamino)-1-(3-fluorphenyl)propan-1-on; 34841-40-2; SCHEMBL770228; CTK8I3431; BDBM50302925; TL8002592
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H18FNO
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| Canonical SMILES |
CC(C(=O)C1=CC(=CC=C1)F)NC(C)(C)C
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| InChI |
1S/C13H18FNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3
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| InChIKey |
CCGVLNAUEKVICK-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dopamine transporter (DAT) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Dopaminergic synapse | |||
| Parkinson's disease | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| Parkinson disease | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| Dopaminergic Neurogenesis | ||||
| Parkinsons Disease Pathway | ||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
| Neurotransmitter Clearance In The Synaptic Cleft | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction. J Med Chem. 2009 Nov 12;52(21):6768-81. | |||
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