Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J6II
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| Former ID |
DCL000713
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| Drug Name |
Azimilide
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| Synonyms |
Azimilide [INN:BAN]; 1-({[5-(4-chlorophenyl)furan-2-yl]methylidene}amino)-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione
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| Drug Type |
Small molecular drug
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| Indication | Atrial fibrillation [ICD-11: BC81.3; ICD-10: I48] | Phase 3 | [1], [2] | |
| Company |
Procter & Gamble
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| Structure |
 |
Download2D MOL |
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| Formula |
C23H28ClN5O3
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| Canonical SMILES |
CN1CCN(CC1)CCCCN2C(=O)CN(C2=O)N=CC3=CC=C(O3)C4=CC=C(C=C4)Cl
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| InChI |
1S/C23H28ClN5O3/c1-26-12-14-27(15-13-26)10-2-3-11-28-22(30)17-29(23(28)31)25-16-20-8-9-21(32-20)18-4-6-19(24)7-5-18/h4-9,16H,2-3,10-15,17H2,1H3/b25-16+
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| InChIKey |
MREBEPTUUMTTIA-PCLIKHOPSA-N
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| CAS Number |
CAS 149908-53-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
854022, 7978750, 14833668, 23996681, 44709202, 50064481, 50070831, 50363598, 57372898, 93300234, 103357886, 117470042, 126626730, 126657825, 126664981, 134339212, 135049470, 137048405, 142105729, 152099929, 163693485, 164788077, 175426919, 179149965, 223442513, 223659937, 226414227, 226414228, 249581702, 252345353
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| ChEBI ID |
CHEBI:34545
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Modulator | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2588). | |||
| REF 2 | New antiarrhythmic agents for atrial fibrillation and atrial flutter. Expert Opin Emerg Drugs. 2005 May;10(2):311-22. | |||
| REF 3 | Azimilide. Drugs. 2000 Feb;59(2):271-7; discussion 278-9. | |||
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