Drug Information
Drug General Information | Top | |||
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Drug ID |
D0J6KZ
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Former ID |
DCL000971
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Drug Name |
S-777469
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Indication | Atopic dermatitis [ICD-11: EA80; ICD-10: L20; ICD-9: 691.8, 692.9] | Phase 2 | [1] | |
Company |
Shionogi USA Inc
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Structure |
Download2D MOL |
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Formula |
C23H27FN2O4
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Canonical SMILES |
CCC1=C(C=C(C(=O)N1CC2=CC=C(C=C2)F)C(=O)NC3(CCCCC3)C(=O)O)C
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InChI |
1S/C23H27FN2O4/c1-3-19-15(2)13-18(20(27)25-23(22(29)30)11-5-4-6-12-23)21(28)26(19)14-16-7-9-17(24)10-8-16/h7-10,13H,3-6,11-12,14H2,1-2H3,(H,25,27)(H,29,30)
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InChIKey |
JIYXOJFSPOFZPY-UHFFFAOYSA-N
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CAS Number |
CAS 885496-53-7
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Cannabinoid receptor 2 (CB2) | Target Info | Agonist | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Class A/1 (Rhodopsin-like receptors) | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Small Ligand GPCRs | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Emerging drugs for atopic dermatitis. Expert Opin Emerg Drugs. 2009 Mar;14(1):165-79. |
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