Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J9VK
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| Former ID |
DIB014733
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| Drug Name |
CM-156
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| Synonyms |
Sigma opioid antagonists (addiction); Sigma opioid antagonists (addiction), University of Mississippi; 2(3H)-benzoxalones and 2(3H)-benzothiazolones (addiction), University of Mississippi
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| Indication | Drug abuse [ICD-11: 6C4G.1Z; ICD-10: F19] | Investigative | [1], [2] | |
| Company |
University of Mississippi
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor sigma 1 (OPRS1) | Target Info | Antagonist | [1], [2] |
| WikiPathways | miR-targeted genes in squamous cell - TarBase | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82. | |||
| REF 2 | Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6. | |||
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