Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0JR9V
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| Former ID |
DIB009055
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| Drug Name |
JBP-1
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| Synonyms |
Trypsinogen/chymotrypsinogen/amylase (metastatic cancer), Propanc
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1], [2] | |
| Company |
Propanc Pty Ltd
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Alpha-glucosidase (GLA) | Target Info | Modulator | [1], [2] |
| Cationic trypsinogen (PRSS1) | Target Info | Modulator | [1], [2] | |
| Chymotrypsin (CTR) | Target Info | Modulator | [1], [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Pancreatic secretion | ||||
| Protein digestion and absorption | ||||
| Influenza A | ||||
| Reactome | Activation of Matrix Metalloproteinases | |||
| Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
| WikiPathways | Activation of Matrix Metalloproteinases | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | US patent application no. 2012,0251,516, PHARMACEUTICAL COMPOSITION FOR TREATING CANCER COMPRISING TRYPSINOGEN AND/OR CHYMOTRYPSINOGEN AND AN ACTIVE AGENT SELECTED FROM A SELENIUM COMPOUND, A VANILLOID COMPOUND AND A CYTOPLASMIC GLYCOLYSIS REDUCTION AGENT. | |||
| REF 2 | EP patent application no. 2490711, A pharmaceutical composition for treating cancer comprising trypsinogen and/or chymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compound and a cytoplasmic glycolysis reduction agent). | |||
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