Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K3MC
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| Former ID |
DIB000496
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| Drug Name |
Lofepramine
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| Synonyms |
Lopramine; DB-2182; Leo-640; WHR-2908A
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| Drug Type |
Small molecular drug
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| Indication | Major depressive disorder [ICD-11: 6A70.3; ICD-10: F32.2] | Approved | [1] | |
| Company |
Leo AB
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H27ClN2O
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| Canonical SMILES |
CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl
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| InChI |
1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3
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| InChIKey |
SAPNXPWPAUFAJU-UHFFFAOYSA-N
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| CAS Number |
CAS 23047-25-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5037067, 7979786, 8152477, 14758154, 29214924, 29223061, 48416179, 49968314, 50111778, 50111779, 50111780, 74809614, 85209645, 91011978, 96024830, 103293068, 104304985, 125536766, 127307216, 127307217, 127307218, 127307219, 129208745, 134223562, 134994073, 135698216, 136350408, 137171622, 142819015, 162023541, 162174605, 162222419, 162955040, 164761617, 175612215, 179150192, 184664934, 198950803, 223365887, 226421368, 241375991, 249924602, 252156597
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| ChEBI ID |
CHEBI:47782
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7551). | |||
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