Drug Information
Drug General Information | Top | |||
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Drug ID |
D0K4FP
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Former ID |
DIB004151
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Drug Name |
AZD-8165
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Synonyms |
AZ-12971554; Thombin inhibitor prodrug (oral), AstraZeneca
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Drug Type |
Small molecular drug
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Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Phase 1 | [1], [2] | |
Company |
AstraZeneca plc
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Structure |
Download2D MOL
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Formula |
C23H21ClFN7O4
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Canonical SMILES |
CCC(=O)OC(C1=CC=C(C=C1)F)C(=O)N2C(CC=N2)C(=O)NCC3=C(C=CC(=C3)Cl)N4C=NN=N4
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InChI |
1S/C23H21ClFN7O4/c1-2-20(33)36-21(14-3-6-17(25)7-4-14)23(35)32-19(9-10-28-32)22(34)26-12-15-11-16(24)5-8-18(15)31-13-27-29-30-31/h3-8,10-11,13,19,21H,2,9,12H2,1H3,(H,26,34)/t19-,21+/m0/s1
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InChIKey |
YUHNXUAATAMVKD-PZJWPPBQSA-N
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CAS Number |
CAS 1201686-72-7
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PubChem Compound ID | ||||
PubChem Substance ID |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7727). | |||
REF 2 | ClinicalTrials.gov (NCT01150812) Oral AZD8165 After Single Oral Ascending Doses in Healthy Male Subjects. U.S. National Institutes of Health. | |||
REF 3 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2362). |
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