Drug Information
Drug General Information | Top | |||
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Drug ID |
D0K5RX
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Former ID |
DNC004980
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Drug Name |
KYS-05050
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Drug Type |
Small molecular drug
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C34H37N5O
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Canonical SMILES |
C1=CC=C(C=C1)CNC(=O)CC2C3=CC=CC=C3NC(=NCCCCCN)N2C4=CC=C(C=C4)C5=CC=CC=C5
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InChI |
1S/C34H37N5O/c35-22-10-3-11-23-36-34-38-31-17-9-8-16-30(31)32(24-33(40)37-25-26-12-4-1-5-13-26)39(34)29-20-18-28(19-21-29)27-14-6-2-7-15-27/h1-2,4-9,12-21,32H,3,10-11,22-25,35H2,(H,36,38)(H,37,40)
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InChIKey |
PHOBNPDRNIKURV-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Voltage-gated calcium channel alpha Cav3.1 (CACNA1G) | Target Info | Inhibitor | [1] |
Voltage-gated calcium channel alpha Cav3.2 (CACNA1H) | Target Info | Inhibitor | [1] | |
KEGG Pathway | MAPK signaling pathway | |||
Calcium signaling pathway | ||||
Circadian entrainment | ||||
Type II diabetes mellitus | ||||
Panther Pathway | Endogenous cannabinoid signaling | |||
GABA-B receptor II signaling | ||||
Nicotine pharmacodynamics pathway | ||||
Pathwhiz Pathway | Muscle/Heart Contraction | |||
Pathway Interaction Database | Regulation of nuclear beta catenin signaling and target gene transcription | |||
Reactome | NCAM1 interactions | |||
WikiPathways | Corticotropin-releasing hormone | |||
NCAM signaling for neurite out-growth | ||||
Nicotine Activity on Chromaffin Cells |
References | Top | |||
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REF 1 | Synthesis and biological evaluation of novel T-type calcium channel blockers. Bioorg Med Chem Lett. 2007 Jan 15;17(2):471-5. |
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