Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K6HD
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| Drug Name |
Azetidine derivative 2
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| Synonyms |
PMID28594589-Compound-TABLE3c11
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| Drug Type |
Small molecular drug
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| Company |
Exelixis
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H17F3IN3O3
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| Canonical SMILES |
C1C(CN1C(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)F)C(=O)NCCO
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| InChI |
1S/C19H17F3IN3O3/c20-13-3-2-12(19(29)26-8-10(9-26)18(28)24-5-6-27)17(16(13)22)25-15-4-1-11(23)7-14(15)21/h1-4,7,10,25,27H,5-6,8-9H2,(H,24,28)
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| InChIKey |
GNOFJPRIPYVPCR-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | ERK activator kinase (MEK) | Target Info | Inhibitor | [1] |
| Target's Patent Info | ERK activator kinase (MEK) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | MEK inhibitors in oncology: a patent review (2015-Present).Expert Opin Ther Pat. 2017 Aug;27(8):887-906. | |||
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