Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0KH3M
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| Former ID |
DNC014824
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| Drug Name |
BIFENOX
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| Synonyms |
BIFENOX; 42576-02-3; Methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate; Modown; Caswell No. 561AA; MC-4379; 5-(2,4-Dichlorophenoxy)-2-nitrobenzoic acid methyl ester; UNII-KSB85XT26Y; Bifenox [ANSI:BSI:ISO]; CCRIS 7158; Benzoic acid, 5-(2,4-dichlorophenoxy)-2-nitro-, methyl ester; HSDB 6567; EINECS 255-894-7; EPA Pesticide Chemical Code 104301; BRN 2170169; KSB85XT26Y; CHEMBL449928; CHEBI:6613; SUSRORUBZHMPCO-UHFFFAOYSA-N; W-110976; Modown 4 flowable; MODOWN(R); AC1L21BG; DSSTox_RID_79477; DSSTox_CID_20320; DSSTox_GSID_40320
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H9Cl2NO5
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| Canonical SMILES |
COC(=O)C1=C(C=CC(=C1)OC2=C(C=C(C=C2)Cl)Cl)[N+](=O)[O-]
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| InChI |
1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3
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| InChIKey |
SUSRORUBZHMPCO-UHFFFAOYSA-N
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| CAS Number |
CAS 42576-02-3
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:6613
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hormone sensitive lipase (LIPE) | Target Info | Inhibitor | [1] |
| BioCyc | Triacylglycerol degradation | |||
| KEGG Pathway | cAMP signaling pathway | |||
| AMPK signaling pathway | ||||
| Insulin signaling pathway | ||||
| Panther Pathway | Triacylglycerol metabolism | |||
| Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |||
| WikiPathways | Insulin Signaling | |||
| Triacylglyceride Synthesis | ||||
| Lipid digestion, mobilization, and transport | ||||
| Adipogenesis | ||||
| Fatty Acid Beta Oxidation | ||||
| AMPK Signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Combining ligand-based pharmacophore modeling, quantitative structure-activity relationship analysis and in silico screening for the discovery of n... J Med Chem. 2008 Oct 23;51(20):6478-94. | |||
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