Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0KJ4U
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| Former ID |
DIB012347
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| Drug Name |
ACEA-1011
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| Synonyms |
Glystatin series member (1011), CoCensys
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| Drug Type |
Small molecular drug
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| Indication | Cerebral infarction [ICD-11: 8B11.5Z; ICD-10: I63] | Terminated | [1] | |
| Company |
Acea Pharmaceuticals Inc
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| Structure |
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Download2D MOL |
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| Formula |
C9H4ClF3N2O2
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| Canonical SMILES |
C1=C(C=C(C2=C1NC(=O)C(=O)N2)Cl)C(F)(F)F
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| InChI |
1S/C9H4ClF3N2O2/c10-4-1-3(9(11,12)13)2-5-6(4)15-8(17)7(16)14-5/h1-2H,(H,14,16)(H,15,17)
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| InChIKey |
JDCKMCIQUXTYQI-UHFFFAOYSA-N
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| CAS Number |
CAS 153504-72-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007916) | |||
| REF 2 | NMDA receptor antagonists, MK-801 and ACEA-1011, prevent the development of tonic pain following subcutaneous formalin. Brain Res. 1993 Jul 2;615(2):331-4. | |||
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