Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0L0MU
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| Former ID |
DNC012254
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| Drug Name |
C-(5H-Dibenzo[a,d]cyclohepten-5-yl)-methylamine
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| Synonyms |
CHEMBL46619; AC1L4MLR; C-(5H-Dibenzo[a,d]cyclohepten-5-yl)-methylamine; SCHEMBL11335219; CTK7E4003; BKZVRYQHIBSITO-UHFFFAOYSA-N; ZINC3622666; BDBM50097217; 5-aminomethyl-5H-dibenzo[a,d]cycloheptene; 5H-Dibenzo[a,d]cycloheptene-5-methanamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H15N
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| Canonical SMILES |
C1=CC=C2C(C3=CC=CC=C3C=CC2=C1)CN
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| InChI |
1S/C16H15N/c17-11-16-14-7-3-1-5-12(14)9-10-13-6-2-4-8-15(13)16/h1-10,16H,11,17H2
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| InChIKey |
BKZVRYQHIBSITO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Exploring the relationship between binding modes of 9-(aminomethyl)-9,10-dihydroanthracene and cyproheptadine analogues at the 5-HT2A serotonin rec... Bioorg Med Chem Lett. 2001 Feb 26;11(4):563-6. | |||
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