Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0L1IB
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| Former ID |
DNC014096
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| Drug Name |
(S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine
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| Synonyms |
UNII-XY1C8J4WGF; XY1C8J4WGF; CHEMBL308538; 186588-98-7; F-A-85380; CHEMBL449437; F-A 85380 Tartrate; (S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine; 2-Fluoro-A 85380; 2-Fluoro-A-85380; A-85380, 2-fluoro; 2-Fluoro-3-(((2S)-2-azetidinyl)methoxy)pyridine; Pyridine, 3-[(2S)-2-azetidinylmethoxy]-2-fluoro-; SCHEMBL1220341; ZINC6525315; FCH858175; BDBM50066788; BDBM50263094; AKOS006285963; ACM209530938; J1.007.103H; 2-fluoro-3-(2(s)-azetidinylmethoxy)pyridine; 3-((S)-1-Azetidin-2-ylmethoxy)-2-fluoro-pyridine; Pyridine, 3-((2S)-2-azetidin
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H11FN2O
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| Canonical SMILES |
C1CNC1COC2=C(N=CC=C2)F
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| InChI |
1S/C9H11FN2O/c10-9-8(2-1-4-12-9)13-6-7-3-5-11-7/h1-2,4,7,11H,3,5-6H2/t7-/m0/s1
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| InChIKey |
GVOOYVOZPRROMP-ZETCQYMHSA-N
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| CAS Number |
CAS 186588-98-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuronal acetylcholine receptor alpha-2 (CHRNA2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Panther Pathway | Nicotinic acetylcholine receptor signaling pathway | |||
| Reactome | Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | |||
| Highly calcium permeable nicotinic acetylcholine receptors | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acety... Bioorg Med Chem. 2009 Jul 1;17(13):4367-77. | |||
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