Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0L1OC
|
|||
| Former ID |
DCL001146
|
|||
| Drug Name |
Anti-LT alpha
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Rheumatoid arthritis [ICD-11: FA20] | Phase 2 | [1] | |
| Company |
Genentech
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Lymphotoxin-alpha (LTA) | Target Info | . | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| NF-kappa B signaling pathway | ||||
| TNF signaling pathway | ||||
| Type I diabetes mellitus | ||||
| HTLV-I infection | ||||
| Herpes simplex infection | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Apoptosis signaling pathway | |||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| IL2 signaling events mediated by STAT5 | ||||
| Reactome | TNFR2 non-canonical NF-kB pathway | |||
| TNFs bind their physiological receptors | ||||
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | ||||
| WikiPathways | Apoptosis | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of Genentech (2011). | |||
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