Drug Information
Drug General Information | Top | |||
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Drug ID |
D0L2KM
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Drug Name |
Quinoline derivative 11
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Synonyms |
PMID27724045-Compound-6
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Drug Type |
Small molecular drug
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Company |
AstraZeneca
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | P2X purinoceptor 7 (P2RX7) | Target Info | Antagonist | [1] |
Voltage-gated potassium channel Kv11.1 (KCNH2) | Target Info | Antagonist | [1] | |
Target's Patent Info | P2X purinoceptor 7 (P2RX7) | Target's Patent Info | [1] | |
Voltage-gated potassium channel Kv11.1 (KCNH2) | Target's Patent Info | [1] | ||
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Pathwhiz Pathway | Muscle/Heart Contraction | |||
Reactome | The NLRP3 inflammasome | |||
Voltage gated Potassium channels | ||||
WikiPathways | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | |||
SIDS Susceptibility Pathways | ||||
Hematopoietic Stem Cell Differentiation | ||||
Potassium Channels |
References | Top | |||
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REF 1 | P2X7 receptor antagonists: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Mar;27(3):257-267. |
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