Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0L3FK
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| Former ID |
DNC001389
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| Drug Name |
SU9516
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| Synonyms |
SU9516; 377090-84-1; SU 9516; SU-9516; AC1NRD9P; 666837-93-0; (3Z)-3-(1H-IMIDAZOL-5-YLMETHYLENE)-5-METHOXY-1H-INDOL-2(3H)-ONE; (Z)-3-((1H-imidazol-5-yl)methylene)-5-methoxyindolin-2-one; (3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-2,3-dihydro-1H-indol-2-one; 3-[1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one; SU9; (Z)-1,3-DIHYDRO-3-(1H-IMIDAZOL-4-YLMETHYLENE)-5-METHOXY-2H-INDOL-2-ONE; 3py1; 3py0; imidazole indolinone driv.; MLS001074893; SCHEMBL1170686; BDBM7238; SCHEMBL1170687; CHEMBL258805
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H11N3O2
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| Canonical SMILES |
COC1=CC2=C(C=C1)NC(=O)C2=CC3=CN=CN3
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| InChI |
1S/C13H11N3O2/c1-18-9-2-3-12-10(5-9)11(13(17)16-12)4-8-6-14-7-15-8/h2-7H,1H3,(H,14,15)(H,16,17)/b11-4-
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| InChIKey |
QNUKRWAIZMBVCU-WCIBSUBMSA-N
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| CAS Number |
CAS 377090-84-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7890624, 8036794, 10318953, 11041562, 14749582, 17405496, 24278633, 26753623, 26753624, 26759572, 29215168, 39321625, 46509014, 47646527, 49655225, 49674687, 57359275, 76715711, 78548907, 85787174, 90341527, 99302840, 103567464, 104234082, 104234084, 113874312, 121514513, 124800707, 124891674, 124891675, 134347529, 134964524, 135304154, 135698919, 139403885, 160966551, 163687283, 165230591, 165231940, 170483742, 170483743, 175607514, 178102667, 179230452, 179235833, 204359717, 223471386, 227407460, 227407461, 241376161
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| ChEBI ID |
CHEBI:113546
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| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6045). | |||
| REF 2 | SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2. Biochem Biophys Res Commun. 2003 Oct 24;310(3):1026-31. | |||
| REF 3 | Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol Sci. 2002 Sep;23(9):417-25. | |||
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