Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0L9OS
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| Former ID |
DNC003510
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| Drug Name |
FR-73966
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| Synonyms |
FR-73966; CHEMBL279073; BDBM50110568; FR73966; 1-[2-(5-Chloro-2-oxo-benzothiazol-3-yl)-acetyl]-piperidine-4-carboxylic acid thiazol-2-ylamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H17ClN4O3S2
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| Canonical SMILES |
C1CN(CCC1C(=O)NC2=NC=CS2)C(=O)CN3C4=C(C=CC(=C4)Cl)SC3=O
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| InChI |
1S/C18H17ClN4O3S2/c19-12-1-2-14-13(9-12)23(18(26)28-14)10-15(24)22-6-3-11(4-7-22)16(25)21-17-20-5-8-27-17/h1-2,5,8-9,11H,3-4,6-7,10H2,(H,20,21,25)
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| InChIKey |
MYSZTUDXDIGAGW-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuropeptide Y receptor type 5 (NPY5R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel potent antagonists of human neuropeptide Y Y5 receptors. Part 3: 7-methoxy-1-hydroxy-1-substituted tetraline derivatives. Bioorg Med Chem Lett. 2002 Mar 11;12(5):799-802. | |||
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