Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0LN9P
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| Former ID |
DIB014745
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| Drug Name |
TELUDIPINE HYDROCHLORIDE
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| Synonyms |
Former USAN >; GR-53992B; GX-1296B; Taludipine hydrochloride < former INNM; Teludipine hydrochloride< Rec INNM; Rac-4-[o-[(E)-2-Carboxyvinyl]phenyl]-2-[(dimethylamino)methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 4-tert-butyl diethyl ester monohydrochloride; Rac-2-(Dimethylaminomethyl)-4-[2-[3-(1,1-dimethylethoxy)-3-oxo-1(E)-propenyl]phenyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester monohydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C28H39ClN2O6
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| Canonical SMILES |
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2C=CC(=O)OC(C)(C)C)C(=O)OCC)CN(C)C)C.Cl
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| InChI |
1S/C28H38N2O6.ClH/c1-9-34-26(32)23-18(3)29-21(17-30(7)8)25(27(33)35-10-2)24(23)20-14-12-11-13-19(20)15-16-22(31)36-28(4,5)6;/h11-16,24,29H,9-10,17H2,1-8H3;1H/b16-15+;
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| InChIKey |
VMZCXIGDNRMWGI-GEEYTBSJSA-N
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| CAS Number |
CAS 108700-03-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Blocker | [1], [2] |
| References | Top | |||
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| REF 1 | Effects of R-enantiomer (GR66234A) and L-enantiomer (GR66235A) of telupidine, a new dihydropyridine derivative, on cell lines displaying the multidrug resistant phenotype. Haematologica. 1994 Jul-Aug;79(4):328-33. | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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