Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M1AE
|
|||
| Former ID |
DNC007122
|
|||
| Drug Name |
N-{4-[(benzylamino)sulfonyl]-1-naphthyl}benzamide
|
|||
| Synonyms |
CHEMBL222111; N-{4-[(benzylamino)sulfonyl]-1-naphthyl}benzamide; SCHEMBL1339724
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C24H20N2O3S
|
|||
| Canonical SMILES |
C1=CC=C(C=C1)CNS(=O)(=O)C2=CC=C(C3=CC=CC=C32)NC(=O)C4=CC=CC=C4
|
|||
| InChI |
1S/C24H20N2O3S/c27-24(19-11-5-2-6-12-19)26-22-15-16-23(21-14-8-7-13-20(21)22)30(28,29)25-17-18-9-3-1-4-10-18/h1-16,25H,17H2,(H,26,27)
|
|||
| InChIKey |
QPJKMKVTEJYYGG-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | C-C chemokine receptor type 8 (CCR8) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Chemokine signaling pathway | ||||
| Viral carcinogenesis | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Reactome | Chemokine receptors bind chemokines | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. J Med Chem. 2007 Feb 8;50(3):566-84. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.