Drug Information
Drug General Information | Top | |||
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Drug ID |
D0M5EW
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Former ID |
DNC007302
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Drug Name |
4-((1H-imidazol-1-yl)methyl)-2H-chromen-2-one
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Synonyms |
CHEMBL427247; 2H-1-Benzopyran-2-one, 4-(1H-imidazol-1-ylmethyl)-; 828265-54-9; Coumarin deriv. 19; BDBM9470; CTK3D6009; DTXSID40460922; ZINC13586713
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C13H10N2O2
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Canonical SMILES |
C1=CC=C2C(=C1)C(=CC(=O)O2)CN3C=CN=C3
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InChI |
1S/C13H10N2O2/c16-13-7-10(8-15-6-5-14-9-15)11-3-1-2-4-12(11)17-13/h1-7,9H,8H2
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InChIKey |
SOWQJCOJWDYZNR-UHFFFAOYSA-N
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CAS Number |
CAS 828265-54-9
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Aromatase (CYP19A1) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Estradiol biosynthesis II | ||||
Estradiol biosynthesis I | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Ovarian steroidogenesis | ||||
NetPath Pathway | FSH Signaling Pathway | |||
Panther Pathway | Androgen/estrogene/progesterone biosynthesis | |||
Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
Reactome | Endogenous sterols | |||
WikiPathways | Metapathway biotransformation | |||
Tryptophan metabolism | ||||
Oxidation by Cytochrome P450 | ||||
Ovarian Infertility Genes | ||||
Metabolism of steroid hormones and vitamin D | ||||
FSH signaling pathway | ||||
Integrated Breast Cancer Pathway | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
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REF 1 | Fast three dimensional pharmacophore virtual screening of new potent non-steroid aromatase inhibitors. J Med Chem. 2009 Jan 8;52(1):143-50. |
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