Drug Information
Drug General Information | Top | |||
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Drug ID |
D0M5TM
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Former ID |
DNC012806
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Drug Name |
8-(3-Fluoro-phenyl)-9-methyl-9H-purin-6-ylamine
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Synonyms |
CHEMBL48682
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H10FN5
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Canonical SMILES |
CN1C(=NC2=C(N=CN=C21)N)C3=CC(=CC=C3)F
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InChI |
1S/C12H10FN5/c1-18-11(7-3-2-4-8(13)5-7)17-9-10(14)15-6-16-12(9)18/h2-6H,1H3,(H2,14,15,16)
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InChIKey |
JXJYLIUAIVDUNX-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Adenosine A2b receptor (ADORA2B) | Target Info | Inhibitor | [1] |
KEGG Pathway | Rap1 signaling pathway | |||
Calcium signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Vascular smooth muscle contraction | ||||
Alcoholism | ||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
TCR Signaling Pathway | ||||
Pathwhiz Pathway | Intracellular Signalling Through Adenosine Receptor A2b and Adenosine | |||
Pathway Interaction Database | C-MYB transcription factor network | |||
Reactome | Adenosine P1 receptors | |||
G alpha (s) signalling events | ||||
Surfactant metabolism | ||||
WikiPathways | Nucleotide GPCRs | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | 2-Alkynyl-8-aryl-9-methyladenines as novel adenosine receptor antagonists: their synthesis and structure-activity relationships toward hepatic gluc... J Med Chem. 2001 Jan 18;44(2):170-9. |
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