Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M7VW
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| Former ID |
DIB007633
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| Drug Name |
GR-65630
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| Synonyms |
GR-65630A
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| Drug Type |
Small molecular drug
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| Indication | Vomiting [ICD-11: MD90; ICD-10: R11; ICD-9: 787] | Terminated | [1] | |
| Company |
Glaxo Group Research Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C16H17N3O
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| Canonical SMILES |
CC1=C(N=CN1)CCC(=O)C2=CC3=CC=CC=C3N2C
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| InChI |
1S/C16H17N3O/c1-11-13(18-10-17-11)7-8-16(20)15-9-12-5-3-4-6-14(12)19(15)2/h3-6,9-10H,7-8H2,1-2H3,(H,17,18)
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| InChIKey |
AQCBJPZFJDPIGL-UHFFFAOYSA-N
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| CAS Number |
CAS 117186-80-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 3 receptor (5HT3R) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003534) | |||
| REF 2 | Binding of the 5-HT3 ligand, [3H]GR65630, to rat area postrema, vagus nerve and the brains of several species. Eur J Pharmacol. 1989 Jan 10;159(2):157-64. | |||
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