Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0M9BY
|
|||
Drug Name |
PMID28394193-Compound-23
|
|||
Drug Type |
Small molecular drug
|
|||
Company |
EPIZYME, INC
|
|||
Structure |
Download2D MOL |
|||
Formula |
C25H31N3O3
|
|||
Canonical SMILES |
CC1=CC(=C(C(=O)N1)CNC(=O)C2=C(N(C3=CC=CC=C32)C(C)C4CCOCC4)C)C
|
|||
InChI |
1S/C25H31N3O3/c1-15-13-16(2)27-24(29)21(15)14-26-25(30)23-18(4)28(22-8-6-5-7-20(22)23)17(3)19-9-11-31-12-10-19/h5-8,13,17,19H,9-12,14H2,1-4H3,(H,26,30)(H,27,29)
|
|||
InChIKey |
HFMSKVHOEPULNV-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Enhancer of zeste homolog 2 (EZH2) | Target Info | Inhibitor | [1] |
Target's Patent Info | Enhancer of zeste homolog 2 (EZH2) | Target's Patent Info | [1] | |
KEGG Pathway | MicroRNAs in cancer | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Reactome | PRC2 methylates histones and DNA | |||
Oxidative Stress Induced Senescence | ||||
PKMTs methylate histone lysines | ||||
WikiPathways | Interactome of polycomb repressive complex 2 (PRC2) | |||
Endoderm Differentiation | ||||
Integrated Pancreatic Cancer Pathway | ||||
Histone Modifications | ||||
Cell Differentiation - meta | ||||
miRs in Muscle Cell Differentiation | ||||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase |
References | Top | |||
---|---|---|---|---|
REF 1 | EZH2 inhibitors: a patent review (2014-2016).Expert Opin Ther Pat. 2017 Jul;27(7):797-813. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.