Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0M9VK
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| Former ID |
DNC005732
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| Drug Name |
1-(6-Methoxy-naphthalen-2-yl)-1H-imidazole
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| Synonyms |
BDBM8918; CHEMBL195629; SCHEMBL4499181; Imidazole-substituted naphthalene 25; ZINC13674484; 1-(6-methoxy-2-naphthyl)-1h-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H12N2O
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| Canonical SMILES |
COC1=CC2=C(C=C1)C=C(C=C2)N3C=CN=C3
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| InChI |
1S/C14H12N2O/c1-17-14-5-3-11-8-13(4-2-12(11)9-14)16-7-6-15-10-16/h2-10H,1H3
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| InChIKey |
IARFMQDFBJWHDO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart fa... J Med Chem. 2005 Oct 20;48(21):6632-42. | |||
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