Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0MB3S
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| Former ID |
DNC003724
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| Drug Name |
7-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamine
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| Synonyms |
7-chloro-1,2,3,4-tetrahydroacridin-9-amine; BRN 0394541; ACRIDINE, 1,2,3,4-TETRAHYDRO-9-AMINO-7-CHLORO-; 6115-67-9; 9-Amino-7-chloro-1,2,3,4-tetrahydroacridine; Tacrine Analogue 3; AC1L2KHB; CHEMBL62084; BDBM8986; DTXSID20210043; ZINC2034186; AKOS011482955; LS-14463
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H13ClN2
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| Canonical SMILES |
C1CCC2=NC3=C(C=C(C=C3)Cl)C(=C2C1)N
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| InChI |
1S/C13H13ClN2/c14-8-5-6-12-10(7-8)13(15)9-3-1-2-4-11(9)16-12/h5-7H,1-4H2,(H2,15,16)
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| InChIKey |
PUKKYURTEBJMKJ-UHFFFAOYSA-N
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| CAS Number |
CAS 6115-67-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acetylcholinesterase (AChE) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Cholinergic synapse | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| Pathwhiz Pathway | Phospholipid Biosynthesis | |||
| Pathway Interaction Database | ATF-2 transcription factor network | |||
| WikiPathways | Monoamine Transport | |||
| Biogenic Amine Synthesis | ||||
| Acetylcholine Synthesis | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory activity of tacrine (Cognex ) derivaties, Bioorg. Med. Chem. Lett. 2(8):861-864 (1992). | |||
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