Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0MH4R
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| Former ID |
DIB021161
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| Drug Name |
visnagin
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| Synonyms |
desmethoxykhellin
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C13H10O4
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| Canonical SMILES |
CC1=CC(=O)C2=C(O1)C=C3C(=C2OC)C=CO3
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| InChI |
1S/C13H10O4/c1-7-5-9(14)12-11(17-7)6-10-8(3-4-16-10)13(12)15-2/h3-6H,1-2H3
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| InChIKey |
NZVQLVGOZRELTG-UHFFFAOYSA-N
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| CAS Number |
CAS 82-57-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
11241, 403790, 933766, 3139927, 5144403, 8154351, 11341724, 11361907, 11364121, 11366683, 11369245, 11372418, 11375389, 11377407, 11485487, 11487309, 11489612, 11491155, 11493580, 11495041, 11537618, 15093363, 25622134, 26613347, 26679673, 26749638, 29204674, 29225665, 46501292, 47291643, 47662797, 47662798, 47811263, 49971776, 50122926, 57323657, 74382080, 77086492, 85209533, 85787097, 87691122, 88783492, 103226076, 103948347, 104312856, 124636297, 124812392, 124891932, 128778353, 134970929
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| ChEBI ID |
CHEBI:10002
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A2b receptor (ADORA2B) | Target Info | Antagonist | [2] |
| Adenosine A3 receptor (ADORA3) | Target Info | Antagonist | [2] | |
| KEGG Pathway | Rap1 signaling pathway | |||
| Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Vascular smooth muscle contraction | ||||
| Alcoholism | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Pathwhiz Pathway | Intracellular Signalling Through Adenosine Receptor A2b and Adenosine | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Adenosine P1 receptors | |||
| G alpha (s) signalling events | ||||
| Surfactant metabolism | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 433). | |||
| REF 2 | Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. J Med Chem. 1996 Jun 7;39(12):2293-301. | |||
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