Drug Information
Drug General Information | Top | |||
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Drug ID |
D0MR9V
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Drug Name |
PMID27998201-Compound-15
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Drug Type |
Small molecular drug
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Indication | Pain [ICD-11: MG30-MG3Z] | Patented | [1] | |
Company |
GRUENENTHAL GMBH [DE
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | Cathepsin K (CTSK) | Target Info | Inhibitor | [1] |
Cathepsin S (CTSS) | Target Info | Inhibitor | [1] | |
Target's Patent Info | Cathepsin K (CTSK) | Target's Patent Info | [1] | |
Cathepsin S (CTSS) | Target's Patent Info | [1] | ||
KEGG Pathway | Lysosome | |||
Osteoclast differentiation | ||||
Toll-like receptor signaling pathway | ||||
Rheumatoid arthritis | ||||
Phagosome | ||||
Antigen processing and presentation | ||||
Tuberculosis | ||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
RANKL Signaling Pathway | ||||
IL2 Signaling Pathway | ||||
Leptin Signaling Pathway | ||||
Reactome | Collagen degradation | |||
Degradation of the extracellular matrix | ||||
Activation of Matrix Metalloproteinases | ||||
Trafficking and processing of endosomal TLR | ||||
MHC class II antigen presentation | ||||
Endosomal/Vacuolar pathway | ||||
Assembly of collagen fibrils and other multimeric structures | ||||
WikiPathways | RANKL/RANK Signaling Pathway | |||
Osteoclast Signaling | ||||
Class I MHC mediated antigen processing & presentation | ||||
Trafficking and processing of endosomal TLR |
References | Top | |||
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REF 1 | Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656. |
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