Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0MX5B
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| Drug Name |
Indazole derivative 5
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| Synonyms |
PMID25656651-Compound-35
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| Drug Type |
Small molecular drug
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| Company |
PFIZER INC
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H18N4OS
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| Canonical SMILES |
CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
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| InChI |
1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+
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| InChIKey |
RITAVMQDGBJQJZ-FMIVXFBMSA-N
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| CAS Number |
CAS 319460-85-0
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:66910
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | ABL T315I mutant (ABL T315I) | Target Info | Inhibitor | [1] |
| Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | ABL T315I mutant (ABL T315I) | Target's Patent Info | [1] | |
| Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I) | Target's Patent Info | [1] | ||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bcr-Abl tyrosine kinase inhibitors: a patent review.Expert Opin Ther Pat. 2015 Apr;25(4):397-412. | |||
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