Drug Information
Drug General Information | Top | |||
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Drug ID |
D0N1CH
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Former ID |
DCL000702
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Drug Name |
Arverapamil
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Synonyms |
Arverapamil; (R)-norverapamil; Agi-003; UNII-3J8P56R04P; (R)-(+)-Nor Verapamil Hydrochloride; 123932-43-4; 3J8P56R04P; Rezular; (+)-norverapamil; (R)-desmethylverapamil; (+)-desmethylverapamil; CHEBI:134082; ZINC13492624; AKOS030532539; Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)amino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, (alphaR)-; UNII-957Z3K3R56 component UPKQNCPKPOLASS-AREMUKBSSA-N
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Drug Type |
Small molecular drug
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Indication | Irritable bowel syndrome [ICD-11: DD91.0; ICD-10: K55-K64, K58; ICD-9: 564.1, 787.91] | Phase 2 | [1] | |
Company |
AGI Therapeutics
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Structure |
Download2D MOL |
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Formula |
C26H36N2O4
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Canonical SMILES |
CC(C)C(CCCNCCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC
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InChI |
1S/C26H36N2O4/c1-19(2)26(18-27,21-9-11-23(30-4)25(17-21)32-6)13-7-14-28-15-12-20-8-10-22(29-3)24(16-20)31-5/h8-11,16-17,19,28H,7,12-15H2,1-6H3/t26-/m1/s1
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InChIKey |
UPKQNCPKPOLASS-AREMUKBSSA-N
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CAS Number |
CAS 123932-43-4
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:134082
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Target and Pathway | Top | |||
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Target(s) | Calcium channel unspecific (CaC) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313. | |||
REF 2 | BJMP 2010;3(4):a342 |
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