Drug Information
Drug General Information | Top | |||
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Drug ID |
D0N1PW
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Former ID |
DNC014612
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Drug Name |
4-Indol-1-ylmethyl-benzamidine
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Synonyms |
1-(4-Amidinobenzyl)indole; 83783-25-9; CHEMBL100569; 4-ABI; 4-Indol-1-ylmethyl-benzamidine; 4-(1h-indol-1-ylmethyl)benzenecarboximidamide; AC1L34FF; AC1Q1U95; CTK5F1124; DTXSID50232637; ZINC5162918; BDBM50027305; AKOS030584119; 4-((1h-indol-1-yl)methyl)benzimidamide; 4-(indol-1-ylmethyl)benzenecarboximidamide; KB-214170; Benzenecarboximidamide,4-(1H-indol-1-ylmethyl)-; Benzenecarboximidamide, 4-(1H-indol-1-ylmethyl)-
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H15N3
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Canonical SMILES |
C1=CC=C2C(=C1)C=CN2CC3=CC=C(C=C3)C(=N)N
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InChI |
1S/C16H15N3/c17-16(18)14-7-5-12(6-8-14)11-19-10-9-13-3-1-2-4-15(13)19/h1-10H,11H2,(H3,17,18)
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InChIKey |
VKEKMIKRPJWXHO-UHFFFAOYSA-N
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CAS Number |
CAS 83783-25-9
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Cationic trypsinogen (PRSS1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Pancreatic secretion | ||||
Protein digestion and absorption | ||||
Influenza A | ||||
Reactome | Activation of Matrix Metalloproteinases | |||
Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
WikiPathways | Activation of Matrix Metalloproteinases |
References | Top | |||
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REF 1 | Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin... J Med Chem. 1983 Feb;26(2):294-8. |
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