Drug Information
Drug General Information | Top | |||
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Drug ID |
D0N4VI
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Former ID |
DNC006343
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Drug Name |
1-(3,4-dihydronaphthalen-2-yl)-1H-imidazole
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Synonyms |
BRN 4745179; 89781-63-5; 1H-Imidazole, 1-(3,4-dihydro-2-naphthalenyl)-; 1-(3,4-Dihydro-2-naphthalenyl)-1H-imidazole; 1-(3,4-dihydronaphthalen-2-yl)-1H-imidazole; 1H-Imidazole,1-(3,4-dihydro-2-naphthalenyl)-; ACMC-20lqcl; Dihydronaphthalene 13; AC1MIBH1; SCHEMBL4513496; CHEMBL208471; BDBM8898; 1-(3,4-DIHYDRO-NAPHTHALEN-2-YL)-1H-IMIDAZOLE; CTK5G3471; DTXSID50237889; ZINC13684552; AKOS006279027; 1-(3,4-dihydronaphthalen-2-yl)imidazole; LS-78473
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C13H12N2
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Canonical SMILES |
C1CC(=CC2=CC=CC=C21)N3C=CN=C3
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InChI |
1S/C13H12N2/c1-2-4-12-9-13(6-5-11(12)3-1)15-8-7-14-10-15/h1-4,7-10H,5-6H2
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InChIKey |
DHUCLDOIXQGVDQ-UHFFFAOYSA-N
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CAS Number |
CAS 89781-63-5
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Mineralocorticoid biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Pathwhiz Pathway | Steroidogenesis | |||
Reactome | Glucocorticoid biosynthesis | |||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Corticotropin-releasing hormone |
References | Top | |||
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REF 1 | Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B... J Med Chem. 2006 Apr 6;49(7):2222-31. |
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