Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0N5KF
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| Drug Name |
Meropenem + vaborbactam
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| Synonyms |
Vabomere; Meropenem / vaborbactam; Meropenem and vaborbactam; Meropenem mixture with vaborbactam; Carbavance
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| Indication | Intra-abdominal infection [ICD-11: 1A40; ICD-10: A09, A09.0] | Approved | [1] | |
| Urinary tract infection [ICD-11: GC08; ICD-10: N39, N39.0] | Approved | [1] | ||
| Company |
The Medicines Company/Rempex Pharmaceuticals
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| Structure |
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Download2D MOL
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| Formula |
C29H41BN4O10S2
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| Canonical SMILES |
B1(C(CCC(O1)CC(=O)O)NC(=O)CC2=CC=CS2)O.CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)N(C)C)C(=O)O)C(C)O
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| InChI |
1S/C17H25N3O5S.C12H16BNO5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;15-11(7-9-2-1-5-20-9)14-10-4-3-8(6-12(16)17)19-13(10)18/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);1-2,5,8,10,18H,3-4,6-7H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+,11-,12-;8-,10-/m10/s1
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| InChIKey |
SDJYWZHQLNEXKV-SSHSFQATSA-N
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| CAS Number |
CAS 2031124-72-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Staphylococcus Beta-lactamase (Stap-coc blaZ) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85. | |||
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