Drug Information
Drug General Information | Top | |||
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Drug ID |
D0N6FH
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Former ID |
DAP001471
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Drug Name |
Dihydroartemisinin
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Synonyms |
Artenimol; Cotecxin; Dihydroartemisinine; Dihydroqinghaosu; Dihydroquinghaosu; Dihydroquinghoasu; VM3352; Artenimol (INN); JAV-110; GNF-PF-5634; (3R,5aS,6R,8aS,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10-ol; [3R-(3.alpha.,5a.beta.,6.beta.,8a.beta.,9.alpha.,10.alpha.,12.beta.,12aR*)]-Decahydro-10-hydroxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4.3-j]-1,2-benzodioxepin; 1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol(Dihydroartemisinin)
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Drug Type |
Small molecular drug
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Indication | Malaria [ICD-11: 1F40-1F45; ICD-10: B50-B64, B54] | Approved | [1] | |
Structure |
Download2D MOL |
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Formula |
C15H24O5
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Canonical SMILES |
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)O)C
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InChI |
1S/C15H24O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-13,16H,4-7H2,1-3H3/t8-,9-,10+,11+,12+,13-,14-,15-/m1/s1
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InChIKey |
BJDCWCLMFKKGEE-ISOSDAIHSA-N
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CAS Number |
CAS 71939-50-9
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PubChem Compound ID | ||||
PubChem Substance ID | ||||
ChEBI ID |
CHEBI:135921
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SuperDrug ATC ID |
P01BE05
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Target and Pathway | Top | |||
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Target(s) | Sarcoplasmic/endoplasmic reticulum calcium ATPase (ATP2A) | Target Info | Inhibitor | [1] |
References | Top | |||
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REF 1 | The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs. Curr Med Chem. 2008;15(2):161-71. |
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