Drug Information
Drug General Information | Top | |||
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Drug ID |
D0ND6T
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Drug Name |
4-(2-cyclohexylethoxy) aniline derivative 2
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Synonyms |
PMID28454500-Compound-88
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Drug Type |
Small molecular drug
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Company |
Korea institute of radiological & medical sciences, S
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Structure |
Download2D MOL |
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Formula |
C18H25NO4
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Canonical SMILES |
C1CCC(CC1)CCOC2=CC=C(C=C2)NC(=O)CCC(=O)O
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InChI |
1S/C18H25NO4/c20-17(10-11-18(21)22)19-15-6-8-16(9-7-15)23-13-12-14-4-2-1-3-5-14/h6-9,14H,1-5,10-13H2,(H,19,20)(H,21,22)
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InChIKey |
NUDKZKXLJIDEDG-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Nuclear factor erythroid 2-related factor 2 (Nrf2) | Target Info | Inhibitor | [1] |
Target's Patent Info | Nuclear factor erythroid 2-related factor 2 (Nrf2) | Target's Patent Info | [1] | |
KEGG Pathway | Protein processing in endoplasmic reticulum | |||
NetPath Pathway | IL5 Signaling Pathway | |||
WikiPathways | Oxidative Stress | |||
Transcriptional activation by NRF2 | ||||
NRF2 pathway | ||||
Nuclear Receptors Meta-Pathway | ||||
Aryl Hydrocarbon Receptor Pathway | ||||
Mesodermal Commitment Pathway | ||||
Aryl Hydrocarbon Receptor | ||||
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
Arylhydrocarbon receptor (AhR) signaling pathway |
References | Top | |||
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REF 1 | Recent progress in the development of small molecule Nrf2 modulators: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Jul;27(7):763-785. |
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